BDBM50382921 CHEMBL2024196::US8569299, 5

SMILES Cc1cc(C2CCN(CC2)C(=O)[C@@H]2CNC[C@H]2c2ccc(F)cc2F)n(n1)-c1ccc(F)c(Cl)c1

InChI Key InChIKey=KGEPDQVEMLHMOP-LEWJYISDSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50382921   

TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50382921(CHEMBL2024196 | US8569299, 5)
Affinity DataIC50:  10.7nMpH: 5.5 T: 2°CAssay Description:The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50382921(CHEMBL2024196 | US8569299, 5)
Affinity DataIC50:  8nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50382921(CHEMBL2024196 | US8569299, 5)
Affinity DataIC50:  11nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed