BDBM50383020 CHEMBL2031277

SMILES COc1cc(cc(OC)c1OC)C(=O)NC(=O)Nc1ccc(C)c(NC(=O)c2ccc(cc2)-c2ccccc2)c1

InChI Key InChIKey=ACUYNCLZSUPUPX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50383020   

TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383020(CHEMBL2031277)
Affinity DataIC50:  24nMAssay Description:Displacement of BODIPY-labelled cyclopamine from human Smo receptor expressed in HEK293 cells after 2 hrs by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383020(CHEMBL2031277)
Affinity DataIC50:  13nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed