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BDBM50383339 CHEMBL2029793

SMILES: CC(C)CCn1ccc(-c2ccc(OCC3CC3)cc2)c(C#N)c1=O

InChI Key: InChIKey=CYOZSBJDLJUVSN-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50383339   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50383339
PNG
(CHEMBL2029793)
Show SMILES CC(C)CCn1ccc(-c2ccc(OCC3CC3)cc2)c(C#N)c1=O
Show InChI InChI=1S/C21H24N2O2/c1-15(2)9-11-23-12-10-19(20(13-22)21(23)24)17-5-7-18(8-6-17)25-14-16-3-4-16/h5-8,10,12,15-16H,3-4,9,11,14H2,1-2H3
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Similars

Article
PubMed
n/an/an/an/a 290n/an/an/an/a



Janssen-Cilag S.A.

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...


J Med Chem 55: 2388-405 (2012)


Article DOI: 10.1021/jm2016864
BindingDB Entry DOI: 10.7270/Q22B9020
More data for this
Ligand-Target Pair