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BDBM50384109 CHEMBL2029350

SMILES: COc1ccc(cc1)N1C(=O)OC(C)(C)C1=O

InChI Key: InChIKey=PXBWMQBSKYVHOR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50384109   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leukocyte elastase


(Homo sapiens (Human))
BDBM50384109
PNG
(CHEMBL2029350)
Show SMILES COc1ccc(cc1)N1C(=O)OC(C)(C)C1=O
Show InChI InChI=1S/C12H13NO4/c1-12(2)10(14)13(11(15)17-12)8-4-6-9(16-3)7-5-8/h4-7H,1-3H3
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



University of Lisbon

Curated by ChEMBL


Assay Description
Inhibition of human neutrophil elastase using chromogenic substrate (N-MeOSuc-Ala-Ala-Pro-Val-p-nitroanilide after 120 mins


Bioorg Med Chem Lett 22: 3993-7 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.093
BindingDB Entry DOI: 10.7270/Q2NZ88PG
More data for this
Ligand-Target Pair