BDBM50384416 CHEMBL2111553::CHEMBL291536::SB-334867

SMILES: Cc1nc2ccc(cc2o1)NC(=O)Nc3ccnc4c3nccc4

InChI Key: InChIKey=AKMNUCBQGHFICM-UHFFFAOYSA-N

Data: 13 KI  7 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50384416   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Orexin receptor type 2 (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Orexin/Hypocretin receptor type 1 (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Orexin receptor type 2 (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Orexin/Hypocretin receptor type 1 (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Orexin/Hypocretin receptor type 1 (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Orexin/Hypocretin receptor type 1 (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Orexin/Hypocretin receptor type 1 (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Orexin/Hypocretin receptor type 1 (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Orexin/Hypocretin receptor type 1 (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Orexin/Hypocretin receptor type 1 (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Orexin/Hypocretin receptor type 1 (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Orexin receptor type 2 (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2a (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Orexin receptor type 2 (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		835	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Orexin receptor type 2 (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Orexin receptor type 2 (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		3.78E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2B (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM50384416 (CHEMBL291536 | CHEMBL2111553 | SB-334867) Show SMILES Show InChI	GoogleScholar	UniChem		<5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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