BDBM50384576 CHEMBL2036808

SMILES CCCCNc1ncc2c(nn(C[C@H]3CC[C@H](N)CC3)c2n1)-c1ccc(F)cc1

InChI Key InChIKey=OGEBRHQLRGFBNV-RZDIXWSQSA-N

Data  1 KI  9 IC50

PDB links: 1 PDB ID matches this monomer.

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50384576   

TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataKi:  4.30nMAssay Description:Inhibition of Mer using EFPIYDFLPAKKK-CONH2 as substrate by Michaelis-Menton equationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of MER (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataIC50:  37nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of Mer expressed in Escherichia coli BL21 (DE3) cells using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electr...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataIC50:  37nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataIC50:  37nMAssay Description:Inhibition of Axl using KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluid capillary electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataIC50:  48nMAssay Description:Inhibition of Tyro3 using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of MER (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataIC50:  48nMAssay Description:Inhibition of TYRO3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataIC50:  141nMAssay Description:Inhibition of Mer autophosphorylation in human 697 cells pretreated for 1 hr before addition of phosphatase inhibitor measured by Western blot analys...More data for this Ligand-Target Pair