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BDBM50384589 CHEMBL2036625

SMILES: CNc1ncc2c(nn(C[C@H]3CC[C@H](O)CC3)c2n1)C(C)=C

InChI Key: InChIKey=WYCSYGHXJGVXDE-HAQNSBGRNA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50384589   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase receptor UFO


(Homo sapiens (Human))
BDBM50384589
PNG
(CHEMBL2036625)
Show SMILES CNc1ncc2c(nn(C[C@H]3CC[C@H](O)CC3)c2n1)C(C)=C
Show InChI InChI=1/C16H23N5O/c1-10(2)14-13-8-18-16(17-3)19-15(13)21(20-14)9-11-4-6-12(22)7-5-11/h8,11-12,22H,1,4-7,9H2,2-3H3,(H,17,18,19)/t11-,12-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 380n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Axl using KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluid capillary electrophoresis assay


ACS Med Chem Lett 3: 129-134 (2012)


Article DOI: 10.1021/ml200239k
BindingDB Entry DOI: 10.7270/Q2F76DMC
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM50384589
PNG
(CHEMBL2036625)
Show SMILES CNc1ncc2c(nn(C[C@H]3CC[C@H](O)CC3)c2n1)C(C)=C
Show InChI InChI=1/C16H23N5O/c1-10(2)14-13-8-18-16(17-3)19-15(13)21(20-14)9-11-4-6-12(22)7-5-11/h8,11-12,22H,1,4-7,9H2,2-3H3,(H,17,18,19)/t11-,12-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 860n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Mer expressed in Escherichia coli BL21 (DE3) cells using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electr...


ACS Med Chem Lett 3: 129-134 (2012)


Article DOI: 10.1021/ml200239k
BindingDB Entry DOI: 10.7270/Q2F76DMC
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM50384589
PNG
(CHEMBL2036625)
Show SMILES CNc1ncc2c(nn(C[C@H]3CC[C@H](O)CC3)c2n1)C(C)=C
Show InChI InChI=1/C16H23N5O/c1-10(2)14-13-8-18-16(17-3)19-15(13)21(20-14)9-11-4-6-12(22)7-5-11/h8,11-12,22H,1,4-7,9H2,2-3H3,(H,17,18,19)/t11-,12-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Tyro3 using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electrophoresis assay


ACS Med Chem Lett 3: 129-134 (2012)


Article DOI: 10.1021/ml200239k
BindingDB Entry DOI: 10.7270/Q2F76DMC
More data for this
Ligand-Target Pair