BDBM50384888 CHEMBL2035810
SMILES Nc1ncnc(Nc2ccc(OCc3ccccn3)c(Cl)c2)c1-c1nc(CNC(=O)C=C)co1
InChI Key InChIKey=PRTPANUTPYMUDM-UHFFFAOYSA-N
Data 22 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 50384888
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Hanmi Research Center
Curated by ChEMBL
Hanmi Research Center
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Hanmi Research Center
Curated by ChEMBL
Hanmi Research Center
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of PIM1More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hanmi Research Center
Curated by ChEMBL
Hanmi Research Center
Curated by ChEMBL
Affinity DataIC50: 22.4nMAssay Description:Inhibition of HER2 preincubated for 10 mins followed by incubation for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Hanmi Research Center
Curated by ChEMBL
Hanmi Research Center
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of HER4 preincubated for 10 mins followed by incubation for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Hanmi Research Center
Curated by ChEMBL
Hanmi Research Center
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of AMPKalpha1More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Hanmi Research Center
Curated by ChEMBL
Hanmi Research Center
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Hanmi Research Center
Curated by ChEMBL
Hanmi Research Center
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of FAKMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Hanmi Research Center
Curated by ChEMBL
Hanmi Research Center
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of Flt1More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Hanmi Research Center
Curated by ChEMBL
Hanmi Research Center
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Hanmi Research Center
Curated by ChEMBL
Hanmi Research Center
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of IGF-1RMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of IRMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase STK11(Homo sapiens (Human))
Hanmi Research Center
Curated by ChEMBL
Hanmi Research Center
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of LKB1More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hanmi Research Center
Curated by ChEMBL
Hanmi Research Center
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of MEK1More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of METMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Hanmi Research Center
Curated by ChEMBL
Hanmi Research Center
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Hanmi Research Center
Curated by ChEMBL
Hanmi Research Center
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of SykMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of wild-type EGFR preincubated for 10 mins followed by incubation for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair