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BDBM50385012 CHEMBL2035387

SMILES: Nc1ccccc1NC(=O)c1ccc(NCC(=O)Nc2ccc(Br)cc2)cc1

InChI Key: InChIKey=QXPHNXUZRCDVFH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385012   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase 1


(Homo sapiens (Human))
BDBM50385012
PNG
(CHEMBL2035387)
Show SMILES Nc1ccccc1NC(=O)c1ccc(NCC(=O)Nc2ccc(Br)cc2)cc1
Show InChI InChI=1S/C21H19BrN4O2/c22-15-7-11-17(12-8-15)25-20(27)13-24-16-9-5-14(6-10-16)21(28)26-19-4-2-1-3-18(19)23/h1-12,24H,13,23H2,(H,25,27)(H,26,28)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



Guru Ghasidas University

Curated by ChEMBL


Assay Description
Inhibition of HDAC1 using Fluor de Lys as substrate by fluorescence analysis


Eur J Med Chem 53: 390-7 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.058
BindingDB Entry DOI: 10.7270/Q25M66QJ
More data for this
Ligand-Target Pair