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BDBM50385281 CHEMBL2035482

SMILES: Brc1ccc2[se]n(CCn3[se]c4ccc(Br)cc4c3=O)c(=O)c2c1

InChI Key: InChIKey=FTVBDRGUOAAJJG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385281   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thioredoxin reductase 1, cytoplasmic


(Rattus norvegicus)
BDBM50385281
PNG
(CHEMBL2035482)
Show SMILES Brc1ccc2[se]n(CCn3[se]c4ccc(Br)cc4c3=O)c(=O)c2c1
Show InChI InChI=1S/C16H10Br2N2O2Se2/c17-9-1-3-13-11(7-9)15(21)19(23-13)5-6-20-16(22)12-8-10(18)2-4-14(12)24-20/h1-4,7-8H,5-6H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.58E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assay


Bioorg Med Chem 20: 3816-27 (2012)


Article DOI: 10.1016/j.bmc.2012.04.033
BindingDB Entry DOI: 10.7270/Q2V69KND
More data for this
Ligand-Target Pair