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BDBM50385876 CHEMBL2042409

SMILES: OC(=O)CN1CCC2(CC1)C(=O)N(c1ccccc21)c1ccccc1

InChI Key: InChIKey=KYZUKYGIXBWSKG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385876   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50385876
PNG
(CHEMBL2042409)
Show SMILES OC(=O)CN1CCC2(CC1)C(=O)N(c1ccccc21)c1ccccc1
Show InChI InChI=1S/C20H20N2O3/c23-18(24)14-21-12-10-20(11-13-21)16-8-4-5-9-17(16)22(19(20)25)15-6-2-1-3-7-15/h1-9H,10-14H2,(H,23,24)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 1.53E+4n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged PHD2 expressed in baculovirus infected insect sf9 cells using biotinyl-DLDLEMLAPYIPMDDDFQL as substrate preincubated with c...


J Med Chem 55: 2945-59 (2012)


Article DOI: 10.1021/jm201542d
BindingDB Entry DOI: 10.7270/Q27945QW
More data for this
Ligand-Target Pair