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BDBM50386224 CHEMBL2043417

SMILES: NCCSC(Cc1ccccc1)(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key: InChIKey=XDRJNNXOEYWSKP-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50386224   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein 1


(Homo sapiens (Human))
BDBM50386224
PNG
(CHEMBL2043417)
Show SMILES NCCSC(Cc1ccccc1)(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C22H21F2NS/c23-20-10-6-18(7-11-20)22(26-15-14-25,16-17-4-2-1-3-5-17)19-8-12-21(24)13-9-19/h1-13H,14-16,25H2
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 588n/an/an/an/an/an/a



University of Strathclyde

Curated by ChEMBL


Assay Description
Inhibition of basal ATPase activity of Eg5 by coupled pyruvate kinase/lactate dehydrogenase assay


Eur J Med Chem 54: 483-98 (2012)


Article DOI: 10.1016/j.ejmech.2012.05.034
BindingDB Entry DOI: 10.7270/Q24B32C6
More data for this
Ligand-Target Pair