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BDBM50386277 CHEMBL2040990

SMILES: Clc1ccc(CC(=O)N2CCCC[C@@H]2C(=O)Nc2ccc(cc2)N2CCOCC2=O)cc1

InChI Key: InChIKey=DWSFRWHJBWETCH-OAQYLSRUSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50386277   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50386277
PNG
(CHEMBL2040990)
Show SMILES Clc1ccc(CC(=O)N2CCCC[C@@H]2C(=O)Nc2ccc(cc2)N2CCOCC2=O)cc1
Show InChI InChI=1S/C24H26ClN3O4/c25-18-6-4-17(5-7-18)15-22(29)28-12-2-1-3-21(28)24(31)26-19-8-10-20(11-9-19)27-13-14-32-16-23(27)30/h4-11,21H,1-3,12-16H2,(H,26,31)/t21-/m1/s1
PDB
MMDB

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Similars

Article
PubMed
n/an/a 2.30E+4n/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a using chromogenic spectrozyme F10a as substrate after 10 mins by spectrophotometry


Eur J Med Chem 54: 771-83 (2012)


Article DOI: 10.1016/j.ejmech.2012.06.032
BindingDB Entry DOI: 10.7270/Q20P1126
More data for this
Ligand-Target Pair