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BDBM50387040 CHEMBL2047018

SMILES: ONC(=O)CCCCCC(=O)Nc1ccc(O)c(c1)C(=O)Nc1ccc(F)c(Cl)c1

InChI Key: InChIKey=WXDPXOBBMKNNFY-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387040   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50387040
PNG
(CHEMBL2047018)
Show SMILES ONC(=O)CCCCCC(=O)Nc1ccc(O)c(c1)C(=O)Nc1ccc(F)c(Cl)c1
Show InChI InChI=1S/C20H21ClFN3O5/c21-15-11-13(6-8-16(15)22)24-20(29)14-10-12(7-9-17(14)26)23-18(27)4-2-1-3-5-19(28)25-30/h6-11,26,30H,1-5H2,(H,23,27)(H,24,29)(H,25,28)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 3.53E+3n/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Inhibition of EGFR derived from human A431 cell membrane assessed as inhibition of poly-Glu-Tyr phosphorylation after 30 mins by ELISA assay


Bioorg Med Chem 20: 4405-12 (2012)


Article DOI: 10.1016/j.bmc.2012.05.034
BindingDB Entry DOI: 10.7270/Q2RV0PQR
More data for this
Ligand-Target Pair