BDBM50387040 CHEMBL2047018

SMILES: ONC(=O)CCCCCC(=O)Nc1ccc(O)c(c1)C(=O)Nc1ccc(F)c(Cl)c1

InChI Key: InChIKey=WXDPXOBBMKNNFY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387040   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50387040 (CHEMBL2047018) Show SMILES ONC(=O)CCCCCC(=O)Nc1ccc(O)c(c1)C(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C20H21ClFN3O5/c21-15-11-13(6-8-16(15)22)24-20(29)14-10-12(7-9-17(14)26)23-18(27)4-2-1-3-5-19(28)25-30/h6-11,26,30H,1-5H2,(H,23,27)(H,24,29)(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of EGFR derived from human A431 cell membrane assessed as inhibition of poly-Glu-Tyr phosphorylation after 30 mins by ELISA assay				Bioorg Med Chem 20: 4405-12 (2012) Article DOI: 10.1016/j.bmc.2012.05.034 BindingDB Entry DOI: 10.7270/Q2RV0PQR
					More data for this Ligand-Target Pair