BDBM50387529 CHEMBL2059909
SMILES CC(C)(C)NS(=O)(=O)c1cncc(c1)-c1ccc2nc(N)nn2c1
InChI Key InChIKey=YKJGGEMOMSRCDT-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50387529
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 25.1nMAssay Description:Inhibition of PI3Kgamma by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of PI3Kdelta by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of C5a-induced AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of fMLP-induced neutrophil migration assay by cell based assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of PI3Kalpha in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 25.1nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of PI3Kdelta in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PI3Kbeta in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of PI3Kalpha by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair