BDBM50387560 CHEMBL2057451::US9359372, DC037017

SMILES COc1cc2CCN3Cc4c(C)cc(C)cc4C[C@H]3c2cc1OC

InChI Key InChIKey=BEZZGCHAIFWOPE-IBGZPJMESA-N

Data  5 KI  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50387560   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387560(CHEMBL2057451 | US9359372, DC037017)
Affinity DataKi:  224nMAssay Description:Displacement of [3H]Spiprone from human dopamine D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387560(CHEMBL2057451 | US9359372, DC037017)
Affinity DataKi:  224nM ΔG°:  -9.22kcal/mole IC50:  1.16E+3nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387560(CHEMBL2057451 | US9359372, DC037017)
Affinity DataKi:  338nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387560(CHEMBL2057451 | US9359372, DC037017)
Affinity DataKi:  338nM ΔG°:  -8.97kcal/mole IC50:  684nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387560(CHEMBL2057451 | US9359372, DC037017)
Affinity DataKi:  1.44E+3nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387560(CHEMBL2057451 | US9359372, DC037017)
Affinity DataEC50:  1.62E+4nMT: 2°CAssay Description:Each medicament was dissolved in serum-free F12 culture medium containing 100 μM of IBMX. CHO cells which can stably express D2 receptor were pre-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387560(CHEMBL2057451 | US9359372, DC037017)
Affinity DataIC50:  1.16E+3nMAssay Description:Displacement of [3H]Spiprone from human dopamine D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387560(CHEMBL2057451 | US9359372, DC037017)
Affinity DataIC50:  2.92E+3nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387560(CHEMBL2057451 | US9359372, DC037017)
Affinity DataIC50:  684nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed