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BDBM50387642 CHEMBL2057491

SMILES: Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3-c3ccccc3)ccc2c1

InChI Key: InChIKey=DBWKEBCQXCVXLS-LEFKRGDZNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387642   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50387642
PNG
(CHEMBL2057491)
Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3-c3ccccc3)ccc2c1
Show InChI InChI=1/C31H29FN2O/c32-25-13-12-23-16-21(10-11-24(23)17-25)20-34-27-14-15-28(34)19-26(18-27)33-31(35)30-9-5-4-8-29(30)22-6-2-1-3-7-22/h1-13,16-17,26-28H,14-15,18-20H2,(H,33,35)/t27-,28-/s2
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Similars

Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Toray Industries Inc

Curated by ChEMBL


Assay Description
Antagonist activity at human CCR3


Bioorg Med Chem Lett 22: 4951-4 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06
More data for this
Ligand-Target Pair