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BDBM50387734 CHEMBL2058886

SMILES: NC(=N)SCc1cccc2c1oc1c(CSC(N)=N)cc(F)cc21

InChI Key: InChIKey=QBCGOAKVJHROLO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387734   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Natural resistance-associated macrophage protein 1


(Homo sapiens (Human))
BDBM50387734
PNG
(CHEMBL2058886)
Show SMILES NC(=N)SCc1cccc2c1oc1c(CSC(N)=N)cc(F)cc21
Show InChI InChI=1S/C16H15FN4OS2/c17-10-4-9(7-24-16(20)21)14-12(5-10)11-3-1-2-8(13(11)22-14)6-23-15(18)19/h1-5H,6-7H2,(H3,18,19)(H3,20,21)
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PC sid
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Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Xenon Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of NRAMP1 expressed in CHO cells


Bioorg Med Chem Lett 22: 5108-13 (2012)


Article DOI: 10.1016/j.bmcl.2012.05.129
BindingDB Entry DOI: 10.7270/Q2QN67TM
More data for this
Ligand-Target Pair