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BDBM50387912 CHEMBL2058673

SMILES: CCc1cnc(nc1)N1CCC(CCCNc2ccc3CCC(=O)c3c2)CC1

InChI Key: InChIKey=DLUDWFPLMUWISJ-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50387912   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucose-dependent insulinotropic receptor


(Mus musculus)
BDBM50387912
PNG
(CHEMBL2058673)
Show SMILES CCc1cnc(nc1)N1CCC(CCCNc2ccc3CCC(=O)c3c2)CC1
Show InChI InChI=1S/C23H30N4O/c1-2-17-15-25-23(26-16-17)27-12-9-18(10-13-27)4-3-11-24-20-7-5-19-6-8-22(28)21(19)14-20/h5,7,14-16,18,24H,2-4,6,8-13H2,1H3
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KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 167n/an/an/an/a



Sanwa Kagaku Kenkyusho Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assay


Bioorg Med Chem Lett 22: 5123-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.05.117
BindingDB Entry DOI: 10.7270/Q2TD9ZC4
More data for this
Ligand-Target Pair
G-protein coupled receptor 119 (GPR119)


(Homo sapiens (Human))
BDBM50387912
PNG
(CHEMBL2058673)
Show SMILES CCc1cnc(nc1)N1CCC(CCCNc2ccc3CCC(=O)c3c2)CC1
Show InChI InChI=1S/C23H30N4O/c1-2-17-15-25-23(26-16-17)27-12-9-18(10-13-27)4-3-11-24-20-7-5-19-6-8-22(28)21(19)14-20/h5,7,14-16,18,24H,2-4,6,8-13H2,1H3
Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 51n/an/an/an/a



Sanwa Kagaku Kenkyusho Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assay


Bioorg Med Chem Lett 22: 5123-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.05.117
BindingDB Entry DOI: 10.7270/Q2TD9ZC4
More data for this
Ligand-Target Pair