BDBM50387926 CHEMBL2058689

SMILES NC(=O)c1cc(Cc2n[nH]c(=O)c3CCCNc23)ccc1F

InChI Key InChIKey=NIMOKLXVCDUKRK-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50387926   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50387926(CHEMBL2058689)
Affinity DataKi:  17nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50387926(CHEMBL2058689)
Affinity DataEC50:  122nMAssay Description:Inhibition of PARP1 in H202-stimulated human C41 cells incubated for 30 mins prior to H2O2-treatment measured after 10 mins by FITC-based immunostain...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed