BDBM50388248 CHEMBL1720543
SMILES FC(F)C(=O)Nc1sc2CNCCc2c1-c1nc2ccccc2s1
InChI Key InChIKey=NRYSIYZIRHQJSQ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50388248
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant APE1 using [35P]-5'-AP-DNA as substrate incubated for 15 mins prior to substrate addition measured after 5 mins by PAGE ana...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human recombinant APE1 after 15 mins by fluorescence based HTS assayMore data for this Ligand-Target Pair