BindingDB logo
myBDB logout

BDBM50388531 CHEMBL2058843

SMILES: CC1(C)NC(=O)Cn2c(Nc3ccc(F)c(Cl)c3)c(nc12)-c1ccc(F)cc1

InChI Key: InChIKey=GJFPMCIOZQKVHI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50388531   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM50388531
PNG
(CHEMBL2058843)
Show SMILES CC1(C)NC(=O)Cn2c(Nc3ccc(F)c(Cl)c3)c(nc12)-c1ccc(F)cc1
Show InChI InChI=1S/C20H17ClF2N4O/c1-20(2)19-25-17(11-3-5-12(22)6-4-11)18(27(19)10-16(28)26-20)24-13-7-8-15(23)14(21)9-13/h3-9,24H,10H2,1-2H3,(H,26,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibition of human ERG channel expressed in CHO cells by patch clamp assay


J Med Chem 55: 4244-73 (2012)


Article DOI: 10.1021/jm300041e
BindingDB Entry DOI: 10.7270/Q21V5G1P
More data for this
Ligand-Target Pair