BDBM50388626 CHEMBL2059435::US9296736, 152::US9593129, Example 152

SMILES: CC[C@@H]([C@H](C)O)N1[C@@H]([C@H](C[C@](C1=O)(C)CC(=O)O)c2cccc(c2)Cl)c3ccc(cc3)Cl

InChI Key: InChIKey=YUALYRLIFVPOHL-UHFFFAOYSA-N

Data: 7 IC50  3 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50388626   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 [1-188] (Human)	BDBM50388626 (CHEMBL2059435 | US9296736, 152 | US9593129, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-188] (Human)	BDBM50388626 (CHEMBL2059435 | US9296736, 152 | US9593129, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Human)	BDBM50388626 (CHEMBL2059435 | US9296736, 152 | US9593129, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Human)	BDBM50388626 (CHEMBL2059435 | US9296736, 152 | US9593129, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Human)	BDBM50388626 (CHEMBL2059435 | US9296736, 152 | US9593129, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Human)	BDBM50388626 (CHEMBL2059435 | US9296736, 152 | US9593129, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 (Human)	BDBM50388626 (CHEMBL2059435 | US9296736, 152 | US9593129, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Human)	BDBM50388626 (CHEMBL2059435 | US9296736, 152 | US9593129, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Human)	BDBM50388626 (CHEMBL2059435 | US9296736, 152 | US9593129, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Human)	BDBM50388626 (CHEMBL2059435 | US9296736, 152 | US9593129, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair