BDBM50389100 CHEMBL2064547

SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cn(CCF)nn1)[C@H](C(C)C)C(=O)NO

InChI Key InChIKey=LOPZANGJCBIBLO-MRXNPFEDSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50389100   

Target72 kDa type IV collagenase(Homo sapiens (Human))
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50389100(CHEMBL2064547)
Affinity DataIC50:  0.130nMAssay Description:Inhibition of MMP2 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50389100(CHEMBL2064547)
Affinity DataIC50:  0.00600nMAssay Description:Inhibition of MMP13 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50389100(CHEMBL2064547)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of MMP9 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50389100(CHEMBL2064547)
Affinity DataIC50:  0.0200nMAssay Description:Inhibition of MMP8 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed