BindingDB logo
myBDB logout

BDBM50389163 CHEMBL2064771

SMILES: CC(C)N1CCCCN(CC1)C(=O)c1ccc2OCCOc2c1

InChI Key: InChIKey=QZULLAJOFDJIPQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50389163   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Homo sapiens (Human))
BDBM50389163
PNG
(CHEMBL2064771)
Show SMILES CC(C)N1CCCCN(CC1)C(=O)c1ccc2OCCOc2c1
Show InChI InChI=1S/C18H26N2O3/c1-14(2)19-7-3-4-8-20(10-9-19)18(21)15-5-6-16-17(13-15)23-12-11-22-16/h5-6,13-14H,3-4,7-12H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.90E+3n/an/an/an/an/an/a



University of Berne

Curated by ChEMBL


Assay Description
Antagonist activity at human alpha7 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-induced current after 30 secs by electrophysiolog...


J Med Chem 55: 4605-18 (2012)


Article DOI: 10.1021/jm300030r
BindingDB Entry DOI: 10.7270/Q2V125VR
More data for this
Ligand-Target Pair