BDBM50389320 CHEMBL2063926

SMILES CSc1ccccc1Nc1nc(nc2c(NCC3CC3)ncnc12)N1CCN(CC1)C1CCNCC1

InChI Key InChIKey=QEMQWMRZJAAQSZ-UHFFFAOYSA-N

Data  31 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 31 hits for monomerid = 50389320   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of SRC by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50:  48nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of NTRK1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ABL1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of JAK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of RPS6KA3 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of AKT1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 13(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of MAPK13 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of PLK3 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 3(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of PAK3 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of CAMK1D by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1B(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ALK4 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ROCK1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of AMPK A1/B1/G1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of DAPK3 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of CDK1/cyclin B by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of PRKACA by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of PIM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of CHEK1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of IRAK4 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of EPHB1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of EGFR by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of CSNK1D by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of INSR by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of GSK3B by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of NEK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of CHEK2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of AURKA by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 26(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of MST4 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of PRKCQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50389320(CHEMBL2063926)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of PDGFRB by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed