BDBM50389382 CHEMBL2064465

SMILES CCN(CCC(=O)N1CCN(CCNc2c3CCCCc3nc3ccccc23)CC1)C1CCCCC1

InChI Key InChIKey=VHCMEFWOVWZTPM-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50389382   

TargetAcetylcholinesterase(Homo sapiens (Human))
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50389382(CHEMBL2064465)
Affinity DataKi:  1.35nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex using acetylthiocholine substrate preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50389382(CHEMBL2064465)
Affinity DataKi:  3.73nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex using acetylthiocholine substrate prein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50389382(CHEMBL2064465)
Affinity DataIC50:  4.97nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine substrate preincubated for 5 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50389382(CHEMBL2064465)
Affinity DataIC50:  41.2nMAssay Description:Inhibition of human plasmatic BChE using butylthiocholne substrate preincubated for 5 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed