BDBM50345705 1-(1-methylethyl)-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::1-isopropyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL1231370::CHEMBL2069954::US10544104, Compound 3::US11247972, Compound 3::US9765037, Compound 3

SMILES: CC(C)n1c2c(c(n1)Cc3cccc4c3cccc4)c(ncn2)N

InChI Key: InChIKey=QFGDRGRJMYSRIW-UHFFFAOYSA-N

Data: 20 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50345705   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Human)	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calmodulin-domain protein kinase 1 (Toxoplasma gondii)	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Calcium/calmodulin dependent protein kinase with a kinas domain and 4 calmodulin-like EF hands (Cryptosporidium parvum (strain Iowa II))	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-dependent protein kinase (Toxoplasma gondii)	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Toxoplasma gondii)	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calcium/calmodulin dependent protein kinase with a kinas domain and 4 calmodulin-like EF hands (Cryptosporidium parvum (strain Iowa II))	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase HCK (Human)	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calmodulin-domain protein kinase 1 (Toxoplasma gondii)	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calmodulin-domain protein kinase 1, putative (Cryptosporidium parvum (strain Iowa II))	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calmodulin-domain protein kinase 1 (Toxoplasma gondii)	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calmodulin-domain protein kinase 1 (Toxoplasma gondii)	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	103	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calmodulin-domain protein kinase 1, putative (Cryptosporidium parvum (strain Iowa II))	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase HCK (Human)	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calcium-dependent protein kinase 1 (Cryptosporidium parvum)	BDBM50345705 (CHEMBL1231370 | CHEMBL2069954 | 1-isopropyl-3-(nap...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair