BDBM50389966 CHEMBL2071206
SMILES CNC(=O)[C@H]1[C@H]2C[C@H](C=C2)[C@H]1Nc1nc(Nc2cnn(C)c2)ncc1C(F)(F)F
InChI Key InChIKey=XXHKWYBEHKUWRK-XXSPCDMZSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50389966
Affinity DataIC50: 45nMAssay Description:Inhibition of Aurora B kinase by HTRF analysis in presence of 1 mM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of KDR by HTRF analysis in presence of 1 mM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >316nMAssay Description:Inhibition of human KDR autophosphorylation expressed in mouse NIH/3T3 cellsMore data for this Ligand-Target Pair