BDBM50390029 CHEMBL2069397
SMILES Fc1ccc(cc1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1
InChI Key InChIKey=PKRXUANONKHENC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50390029
Affinity DataKi: 410nMAssay Description:Displacement of [3H]NAM from mGluR5More data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:Displacement of [3H]NAM from mGluR5More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR methodMore data for this Ligand-Target Pair
Affinity DataEC50: 10.7nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Lundbeck Research Usa
Curated by ChEMBL
Lundbeck Research Usa
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10.7nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Lundbeck Research Usa
Curated by ChEMBL
Lundbeck Research Usa
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair