BDBM50390066 CHEMBL2069396
SMILES Clc1cccc(c1)-c1noc(CCN2C(=O)CCc3ccc(Cl)cc23)n1
InChI Key InChIKey=MCAKTFKDPVNZIW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50390066
Affinity DataIC50: 550nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR methodMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR methodMore data for this Ligand-Target Pair