BDBM50390269 CHEMBL2070424

SMILES CCN(CC)CCOc1ccc(cc1)N1C(=S)S\C(=C/c2ccc(Oc3ccc(cc3)C(N)=O)cc2)C1=O

InChI Key InChIKey=VAEBUOVUQWFZTP-XHPQRKPJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50390269   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Mus musculus)
Korea University

Curated by ChEMBL
LigandPNGBDBM50390269(CHEMBL2070424)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of IKKbeta in mouse CIA model spelonocytes assessed as inhibition of TNFalpha production after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50390269(CHEMBL2070424)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of IKKbeta using 5FAM-GRHDSGLDSMK-NH2 as substrate incubated for 10 mins prior to substrate addition by IMAP-TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed