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BDBM50390302 CHEMBL2070764

SMILES: FC(F)(F)c1nc(NCCCc2ccccc2)c2nnn(C[C@H]3CCCO3)c2n1

InChI Key: InChIKey=ALWFSHXFHSOTSC-CQSZACIVSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390302   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 8


(Homo sapiens (Human))
BDBM50390302
PNG
(CHEMBL2070764)
Show SMILES FC(F)(F)c1nc(NCCCc2ccccc2)c2nnn(C[C@H]3CCCO3)c2n1
Show InChI InChI=1S/C19H21F3N6O/c20-19(21,22)18-24-16(23-10-4-8-13-6-2-1-3-7-13)15-17(25-18)28(27-26-15)12-14-9-5-11-29-14/h1-3,6-7,14H,4-5,8-12H2,(H,23,24,25)/t14-/m1/s1
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PC sid
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Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE8B expressed in Sf9 insect cells


Bioorg Med Chem Lett 22: 5721-6 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.079
BindingDB Entry DOI: 10.7270/Q2J67J0X
More data for this
Ligand-Target Pair