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BDBM50390328 CHEMBL2070610

SMILES: Nc1nc(nc2n(C[C@@H]3CCN(Cc4nccs4)C3)nnc12)C1CC1

InChI Key: InChIKey=DQAIWNYIUVKEPK-SNVBAGLBSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390328   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 8


(Homo sapiens (Human))
BDBM50390328
PNG
(CHEMBL2070610)
Show SMILES Nc1nc(nc2n(C[C@@H]3CCN(Cc4nccs4)C3)nnc12)C1CC1
Show InChI InChI=1S/C16H20N8S/c17-14-13-16(20-15(19-14)11-1-2-11)24(22-21-13)8-10-3-5-23(7-10)9-12-18-4-6-25-12/h4,6,10-11H,1-3,5,7-9H2,(H2,17,19,20)/t10-/m1/s1
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 206n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE8B expressed in Sf9 insect cells


Bioorg Med Chem Lett 22: 5721-6 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.079
BindingDB Entry DOI: 10.7270/Q2J67J0X
More data for this
Ligand-Target Pair