BDBM50390498 CHEMBL2071612

SMILES CC(C)(C)c1ccc(Nc2nc3ccc(cc3[nH]2)C#N)cc1

InChI Key InChIKey=BQPYYTDDPDJCGA-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50390498   

TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390498(CHEMBL2071612)
Affinity DataIC50:  7.58E+3nMAssay Description:Inhibition of CK1alpha by Lance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform gamma-2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390498(CHEMBL2071612)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblottingMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390498(CHEMBL2071612)
Affinity DataIC50:  4.45E+4nMAssay Description:Inhibition of GSK3beta by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390498(CHEMBL2071612)
Affinity DataIC50:  2.62E+3nMAssay Description:Inhibition of CK1delta by Lance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed