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BDBM50390587 CHEMBL2069492

SMILES: Cc1ccc(C[C@H](N)C(=O)Nc2cc(c[nH]c2=O)-c2ccncc2)cc1

InChI Key: InChIKey=NTZHGDLSLGWDGT-KRWDZBQOSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390587   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Probable G-protein coupled receptor 142


(Homo sapiens (Human))
BDBM50390587
PNG
(CHEMBL2069492)
Show SMILES Cc1ccc(C[C@H](N)C(=O)Nc2cc(c[nH]c2=O)-c2ccncc2)cc1
Show InChI InChI=1S/C20H20N4O2/c1-13-2-4-14(5-3-13)10-17(21)19(25)24-18-11-16(12-23-20(18)26)15-6-8-22-9-7-15/h2-9,11-12,17H,10,21H2,1H3,(H,23,26)(H,24,25)/t17-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 6.60E+3n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...


Bioorg Med Chem Lett 22: 5942-7 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.063
BindingDB Entry DOI: 10.7270/Q2VH5PXT
More data for this
Ligand-Target Pair