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BDBM50390799 CHEMBL2070633

SMILES: COc1ccc2nnc3c(C)nc(-c4ccc(F)cc4C)n3c2n1

InChI Key: InChIKey=OSQYQSYCOOIVGE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390799   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM50390799
PNG
(CHEMBL2070633)
Show SMILES COc1ccc2nnc3c(C)nc(-c4ccc(F)cc4C)n3c2n1
Show InChI InChI=1S/C17H14FN5O/c1-9-8-11(18)4-5-12(9)16-19-10(2)15-22-21-13-6-7-14(24-3)20-17(13)23(15)16/h4-8H,1-3H3
PDB
MMDB

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Similars

Article
PubMed
n/an/a 45.9n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis


Bioorg Med Chem Lett 22: 5876-84 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413
More data for this
Ligand-Target Pair