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BDBM50390815 CHEMBL2070652

SMILES: COc1cc(OC)c2nnc3c(C)nc(-c4cnccc4C)n3c2c1

InChI Key: InChIKey=MSAZJEUMUSIUHQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390815   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM50390815
PNG
(CHEMBL2070652)
Show SMILES COc1cc(OC)c2nnc3c(C)nc(-c4cnccc4C)n3c2c1
Show InChI InChI=1S/C18H17N5O2/c1-10-5-6-19-9-13(10)18-20-11(2)17-22-21-16-14(23(17)18)7-12(24-3)8-15(16)25-4/h5-9H,1-4H3
PDB
MMDB

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Similars

Article
PubMed
n/an/a 4.16n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis


Bioorg Med Chem Lett 22: 5876-84 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413
More data for this
Ligand-Target Pair