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BDBM50391082 CHEMBL2087353

SMILES: Brc1cccc(Nc2ncnc3cc4OCCOCCOc4cc23)c1

InChI Key: InChIKey=ITIUGXULOLVCPV-UHFFFAOYSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50391082   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50391082
PNG
(CHEMBL2087353)
Show SMILES Brc1cccc(Nc2ncnc3cc4OCCOCCOc4cc23)c1
Show InChI InChI=1S/C18H16BrN3O3/c19-12-2-1-3-13(8-12)22-18-14-9-16-17(10-15(14)20-11-21-18)25-7-5-23-4-6-24-16/h1-3,8-11H,4-7H2,(H,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 55n/an/an/an/an/an/a



Zhejiang Betapharma

Curated by ChEMBL


Assay Description
Inhibition of EGFR using GST-Crk as substrate assessed as phosphorylated Crk level after 20 mins by SDS-PAGE analysis


Bioorg Med Chem Lett 22: 6301-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.067
BindingDB Entry DOI: 10.7270/Q2NP25HZ
More data for this
Ligand-Target Pair