BDBM50391267 CHEMBL1246::Mono-N-Acetyl Dapsone

SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)c1ccc(N)cc1

InChI Key InChIKey=WDOCBIHNYYQINH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50391267   

Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM50391267(CHEMBL5289747)
Affinity DataEC50:  12nMAssay Description:Beta-1 adrenergic receptor activitation measured by isoprenaline-induced positive inotropic effect in guinea pig left atriumMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM50391267(CHEMBL5289747)
Affinity DataIC50: >4.50E+4nMAssay Description:Antagonistic activity against Thromboxane A2 receptor in guinea pig trachea in the presence of 11,9-epoxymethano-PGH2More data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50391267(CHEMBL5289747)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails