BDBM50392277 CHEMBL2153645
SMILES [#6]-[#6][C@@]1([#8])[#6](=O)-[#8]-[#6]-c2c1cc1-c3nc4ccc(-[#8]-[#6](=O)-[#7]-5-[#6]-[#6]-[#7](-[#6]-[#6]-5)-[#6](=O)-c5ccc(-[#6]-[#8]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](=O)-[#7]-6-[#6]-[#6]-[#7](-[#6]-[#6]-6)-c6cccc(c6)\[#7]=[#6]-6/[#7]-[#6]-[#6]-[#6]-[#7]-6)-[#6](-[#8])=O)cc5)cc4c(\[#6]=[#7]\[#8]C([#6])([#6])[#6])c3-[#6]-n1c2=O
InChI Key InChIKey=MJIZYHGNHUTXIR-WBRXUAKLSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50392277
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Affinity DataIC50: 4.83nMAssay Description:Displacement of [125I]echistatin from integrin alpha5beta3 after 3 hrs by gamma counterMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin expressed in PC3 cellsMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin over expressed in A2780 cellsMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Affinity DataIC50: 0.760nMAssay Description:Displacement of [125I]echistatin from integrin alpha5beta5 after 3 hrs by gamma counterMore data for this Ligand-Target Pair