BDBM50392668 CHEMBL2153830

SMILES Cc1c(cc(-c2ccc(cc2)S(C)(=O)=O)n1-c1cccc(F)c1)C(N)C(=O)OCCCO

InChI Key InChIKey=LIXWOSZNRMANQZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50392668   

TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50392668(CHEMBL2153830)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-induced mouse J774 cells by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50392668(CHEMBL2153830)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of COX1-mediated PGE2 production in mouse J774 cells preincubated for 15 mins measured after 30 mins by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed