BindingDB logo
myBDB logout

BDBM50392920 CHEMBL2152218

SMILES: Cc1c(Cl)cccc1S(=O)(=O)N1CCC[C@@H]1C(=O)NC1CCCCC1

InChI Key: InChIKey=HJDHXRWDPKGUID-XISACWJONA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50392920   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (Human))
BDBM50392920
PNG
(CHEMBL2152218)
Show SMILES Cc1c(Cl)cccc1S(=O)(=O)N1CCC[C@@H]1C(=O)NC1CCCCC1
Show InChI InChI=1/C18H25ClN2O3S/c1-13-15(19)9-5-11-17(13)25(23,24)21-12-6-10-16(21)18(22)20-14-7-3-2-4-8-14/h5,9,11,14,16H,2-4,6-8,10,12H2,1H3,(H,20,22)/t16-/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.40E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human 11betaHSD1 by scintillation proximity assay


ACS Med Chem Lett 3: 793-798 (2012)


Article DOI: 10.1021/ml300144n
BindingDB Entry DOI: 10.7270/Q2K938NZ
More data for this
Ligand-Target Pair