BDBM50393458 CHEMBL2159686

SMILES CS(=O)(=O)CC[C@H]1OCC[C@]2([C@@H]1COc1c(F)ccc(F)c21)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=AMXSRXZYBDALJG-FQELHTAISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50393458   

TargetPresenilin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393458(CHEMBL2159686)
Affinity DataIC50:  377nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed