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BDBM50393669 CHEMBL2158903

SMILES: S=C(Nc1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1

InChI Key: InChIKey=IKCLESDMCSMYBE-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50393669   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoglyceride lipase


(Homo sapiens (Human))
BDBM50393669
PNG
(CHEMBL2158903)
Show SMILES S=C(Nc1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H25N3S/c28-24(25-22-14-8-3-9-15-22)27-18-16-26(17-19-27)23(20-10-4-1-5-11-20)21-12-6-2-7-13-21/h1-15,23H,16-19H2,(H,25,28)
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counter


J Med Chem 55: 5774-83 (2012)


Article DOI: 10.1021/jm3006004
BindingDB Entry DOI: 10.7270/Q2TD9ZF1
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50393669
PNG
(CHEMBL2158903)
Show SMILES S=C(Nc1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H25N3S/c28-24(25-22-14-8-3-9-15-22)27-18-16-26(17-19-27)23(20-10-4-1-5-11-20)21-12-6-2-7-13-21/h1-15,23H,16-19H2,(H,25,28)
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH assessed as conversion of [3H]AEA to [3H]ethanolamine after 10 mins by liquid scintillation counter


J Med Chem 55: 5774-83 (2012)


Article DOI: 10.1021/jm3006004
BindingDB Entry DOI: 10.7270/Q2TD9ZF1
More data for this
Ligand-Target Pair