BDBM50394384 CHEMBL2159803
SMILES Brc1ccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)cc1
InChI Key InChIKey=QRUVSFSFNFOCQH-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50394384
Affinity DataIC50: 9nMAssay Description:Inhibition of human MAGL using 4-Nitrophenylacetate substrate incubated for 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair