BDBM50394384 CHEMBL2159803

SMILES Brc1ccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)cc1

InChI Key InChIKey=QRUVSFSFNFOCQH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50394384   

TargetMonoglyceride lipase(Homo sapiens (Human))
Jamia Hamdard (Hamdard University)

Curated by ChEMBL
LigandPNGBDBM50394384(CHEMBL2159803)
Affinity DataIC50:  9nMAssay Description:Inhibition of human MAGL using 4-Nitrophenylacetate substrate incubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Jamia Hamdard (Hamdard University)

Curated by ChEMBL
LigandPNGBDBM50394384(CHEMBL2159803)
Affinity DataIC50:  9nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50394384(CHEMBL2159803)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed