BDBM50395122 CHEMBL2163561

SMILES COP(=O)(OC)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCC3)nc(Cl)nc12

InChI Key InChIKey=XOTIHNLKQLTTCS-XNIJJKJLSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50395122   

TargetAdenosine receptor A1(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50395122(CHEMBL2163561)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]2-chloro-N6-cyclopentyladenosine from human A1ARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50395122(CHEMBL2163561)
Affinity DataKi:  450nMAssay Description:Displacement of [3H]2-chloro-N6-cyclopentyladenosine from human A3ARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50395122(CHEMBL2163561)
Affinity DataKi:  4.70E+3nMAssay Description:Displacement of [3H]2-chloro-N6-cyclopentyladenosine from human A2ARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50395122(CHEMBL2163561)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at human A1AR expressed in HEK293T/17 cells assessed as inhibition of isoproterenol-induced cAMP accumulation incubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50395122(CHEMBL2163561)
Affinity DataEC50:  520nMAssay Description:Agonist activity at human A1AR assessed as induction of Ca2+ ion mobilization by orthogonal functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed