BDBM50395170 CHEMBL2163958

SMILES: Cc1cc2OCC(c3ccccc3)n3cc(C(=O)NC4CCCCC4)c(=O)c(c1)c23

InChI Key: InChIKey=LUTFEJUSDOPSHW-UHFFFAOYSA-N

Data: 4 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50395170   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50395170 (CHEMBL2163958) Show SMILES Cc1cc2OCC(c3ccccc3)n3cc(C(=O)NC4CCCCC4)c(=O)c(c1)c23 Show InChI InChI=1S/C25H26N2O3/c1-16-12-19-23-22(13-16)30-15-21(17-8-4-2-5-9-17)27(23)14-20(24(19)28)25(29)26-18-10-6-3-7-11-18/h2,4-5,8-9,12-14,18,21H,3,6-7,10-11,15H2,1H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in CHO cell membranes incubated for 60 mins by scintillation counting				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM50395170 (CHEMBL2163958) Show SMILES Cc1cc2OCC(c3ccccc3)n3cc(C(=O)NC4CCCCC4)c(=O)c(c1)c23 Show InChI InChI=1S/C25H26N2O3/c1-16-12-19-23-22(13-16)30-15-21(17-8-4-2-5-9-17)27(23)14-20(24(19)28)25(29)26-18-10-6-3-7-11-18/h2,4-5,8-9,12-14,18,21H,3,6-7,10-11,15H2,1H3,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB2 receptor in Sprague-Dawley rat spleen by scintillation counting				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50395170 (CHEMBL2163958) Show SMILES Cc1cc2OCC(c3ccccc3)n3cc(C(=O)NC4CCCCC4)c(=O)c(c1)c23 Show InChI InChI=1S/C25H26N2O3/c1-16-12-19-23-22(13-16)30-15-21(17-8-4-2-5-9-17)27(23)14-20(24(19)28)25(29)26-18-10-6-3-7-11-18/h2,4-5,8-9,12-14,18,21H,3,6-7,10-11,15H2,1H3,(H,26,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cell membranes incubated for 90 mins by scintillation counting				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50395170 (CHEMBL2163958) Show SMILES Cc1cc2OCC(c3ccccc3)n3cc(C(=O)NC4CCCCC4)c(=O)c(c1)c23 Show InChI InChI=1S/C25H26N2O3/c1-16-12-19-23-22(13-16)30-15-21(17-8-4-2-5-9-17)27(23)14-20(24(19)28)25(29)26-18-10-6-3-7-11-18/h2,4-5,8-9,12-14,18,21H,3,6-7,10-11,15H2,1H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.57E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat brain by scintillation counting				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50395170 (CHEMBL2163958) Show SMILES Cc1cc2OCC(c3ccccc3)n3cc(C(=O)NC4CCCCC4)c(=O)c(c1)c23 Show InChI InChI=1S/C25H26N2O3/c1-16-12-19-23-22(13-16)30-15-21(17-8-4-2-5-9-17)27(23)14-20(24(19)28)25(29)26-18-10-6-3-7-11-18/h2,4-5,8-9,12-14,18,21H,3,6-7,10-11,15H2,1H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-induced cAMP accumulation				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair