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BDBM50395291 CHEMBL2163619

SMILES: N[C@H]1CC[C@@H](CC1)Nc1cc(NCc2ccccc2)n2nccc2n1

InChI Key: InChIKey=QWQBUHHFXHTFDX-WKILWMFISA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395291   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
MAP kinase-activated protein kinase 2


(Homo sapiens (Human))
BDBM50395291
PNG
(CHEMBL2163619)
Show SMILES N[C@H]1CC[C@@H](CC1)Nc1cc(NCc2ccccc2)n2nccc2n1
Show InChI InChI=1S/C19H24N6/c20-15-6-8-16(9-7-15)23-17-12-19(25-18(24-17)10-11-22-25)21-13-14-4-2-1-3-5-14/h1-5,10-12,15-16,21H,6-9,13,20H2,(H,23,24)/t15-,16-
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PC cid
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Similars

Article
PubMed
n/an/a 7.00E+3n/an/an/an/an/an/a



Teijin Pharma Ltd.

Curated by ChEMBL


Assay Description
Inhibition of MAPKAP-K2 using KKLNRTLSVA as substrate and [33P]-gamma-ATP after 30 mins by liquid scintillation counter


J Med Chem 55: 6700-15 (2012)


Article DOI: 10.1021/jm300411k
BindingDB Entry DOI: 10.7270/Q20K29PX
More data for this
Ligand-Target Pair