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BDBM50395300 CHEMBL2163978

SMILES: CCOc1ccc(Nc2c(C)c(NCCCN)nc3ccnn23)cc1

InChI Key: InChIKey=OIPIROSCRJXFJE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395300   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
MAP kinase-activated protein kinase 2


(Homo sapiens (Human))
BDBM50395300
PNG
(CHEMBL2163978)
Show SMILES CCOc1ccc(Nc2c(C)c(NCCCN)nc3ccnn23)cc1
Show InChI InChI=1S/C18H24N6O/c1-3-25-15-7-5-14(6-8-15)22-18-13(2)17(20-11-4-10-19)23-16-9-12-21-24(16)18/h5-9,12,22H,3-4,10-11,19H2,1-2H3,(H,20,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.70E+3n/an/an/an/an/an/a



Teijin Pharma Ltd.

Curated by ChEMBL


Assay Description
Inhibition of MAPKAP-K2 using KKLNRTLSVA as substrate and [33P]-gamma-ATP after 30 mins by liquid scintillation counter


J Med Chem 55: 6700-15 (2012)


Article DOI: 10.1021/jm300411k
BindingDB Entry DOI: 10.7270/Q20K29PX
More data for this
Ligand-Target Pair